First days of gameplay I used the onboard intel GPU alongside the fix provided. Didn't do the trick. Boarding crash almost all the time. Got angry. Fresh install, used only the Nvidia GPU, same crash in same place, the cargo area. I can only speculate... anything could be faulty, including my saves, the various ship types, the looting mechanics, but one thing i'm sure of, at the moment the game is pretty much unplayable, because naval battle and boarding subsequently play such an important part in the overall appeal of the game. Boarding is kind of hard as it is, with them angry pirates rushing towards you, with demigod hitpoints while your own idiotic party members have hit boxes the size of a house, and do a very good job at preventing you from reaching the enemy. Even that is manageable, wasting hours on capturing a ship isn't. Still, I think I pretty much want to continue playing this game and I do wan't to know if there is someone with the heavy ship boarding/capturing combat oriented play style and what setup or configuration works for you.
Which version of the game are you using? Though I'm still getting the same problem of crashing, it's not all the time, and it's less frequent in Beta 3.4 (or, for that matter, Beta 3.3) than it was in Beta 3.1.
In spite of that, I do play a very combat-heavy game with lots of boarding and looting. It's the looting which sometimes causes the problem. It's almost as if the game is determined that a particular battle will end with a crash - I usually save game just before going into a battle for exactly this reason, and if the game crashes, it will probably crash after I reload the saved game. On one occasion I saved before one battle, it
didn't crash and I succeeded in looting everything, then I forgot to save before the next battle and it did crash. Reload, fight first battle, no crash, proceed to second battle, it crashed again. When this happens, I reload, fight the battle again, but refrain from looting corpses or chests - annoying, but that's guaranteed to prevent a crash, at least for me. Nevertheless, I'm able to loot often enough that I've never bought any sort of medicine, and all the weapons and armour in the ship's locker are second-hand, so to speak.
Initially the crew are expendable drones whose only function in their brief lives is to keep some of the enemy occupied long enough for you to finish off your first few, then you can take on the rest of the enemy. You
really need good Melee skill and preferably half-decent armour, and so do your officers - anyone with Melee skill less than 4 should not be allowed into a boarding action. Later on, when you and your officers have better armour and swords, and you've put a good load of armour and weapons into the ship's locker, your crew can survive battle. And at this point you don't want any officer with Melee less than 6 involved in boarding.